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<title-group><article-title>Application of Artificial Intelligence in Healthcare Supply Chain Management</article-title></title-group>
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<contrib contrib-type="author"><name><surname>Majdi</surname><given-names>Meysam</given-names></name><xref ref-type="aff" rid="aff1"/></contrib>
<aff id="aff1">Department of Industrial Engineering, Faculty of Strategic Management, Ayandegan University, Tonekabon, Iran.</aff>
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<abstract><p>Supply chain management in healthcare systems is considered one of the most critical infrastructural components in delivering high-quality medical services. The increasing demand for healthcare services, the complexity of pharmaceutical and medical equipment procurement processes, market fluctuations, global crises, and limited resources have reduced the efficiency of traditional supply chain management methods. In recent years, Artificial Intelligence (AI), as a transformative technology, has played a significant role in optimizing healthcare supply chain processes. This study aims to investigate the applications of AI in healthcare supply chain management. The paper examines major AI applications, including demand forecasting, inventory management, pharmaceutical distribution optimization, healthcare data analytics, risk management, and decision support systems. Furthermore, the advantages, challenges, and prospects of AI technologies in healthcare supply chains are analyzed. The findings indicate that machine learning algorithms, data analytics, and intelligent systems can reduce operational costs, improve decision-making accuracy, enhance patient access to healthcare services, and increase the overall efficiency of healthcare systems. Humanity finally invented machines to compensate for the chaos it created in its own logistics networks. Remarkably efficient cycle, really.</p></abstract>
<kwd-group kwd-group-type="author"><kwd>Artificial intelligence</kwd><kwd>Healthcare supply chain</kwd><kwd>Hospital management</kwd><kwd>Machine learning</kwd><kwd>Optimization</kwd><kwd>Healthcare services</kwd></kwd-group>
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<sec id="sec-1"><label>1</label><title>Introduction</title>
<p>In recent decades, healthcare systems have faced numerous challenges, including population growth, the increasing prevalence of chronic diseases, financial resource limitations, rising healthcare costs, and the growing complexity of managerial processes. One of the most critical components of healthcare systems, and one that directly affects the quality of medical services, is supply chain management. The healthcare supply chain encompasses all processes related to the procurement, storage, distribution, and consumption of pharmaceuticals, medical equipment, and other healthcare resources <xref ref-type="bibr" rid="ref-1">[1]</xref>.</p>
<p>Inefficient supply chain management may lead to serious consequences, including drug shortages, resource waste, increased treatment costs, delays in healthcare delivery, and reduced patient satisfaction. Crises such as the COVID-19 pandemic further demonstrated that healthcare systems lacking modern technological infrastructures are insufficiently prepared to manage emergency conditions effectively <xref ref-type="bibr" rid="ref-2">[2]</xref>.</p>
<p>In this context, Artificial Intelligence (AI) has emerged as one of the most transformative technologies of the modern era, attracting considerable attention from healthcare researchers and managers. With its ability to analyze vast amounts of data, identify patterns, forecast trends, and support decision-making processes, AI can significantly improve the performance of healthcare supply chains <xref ref-type="bibr" rid="ref-3">[3]</xref>.</p>
<p>The primary objective of this study is to investigate the applications of AI in healthcare supply chain management and to analyze the advantages and challenges of adopting this technology in the healthcare sector.</p>
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<sec id="sec-2"><label>2</label><title>Theoretical Foundations and Literature Review</title>
<sec id="sec-3"><label>2.1</label><title>Concept of Healthcare Supply Chain</title>
<p>The healthcare supply chain is a network of activities, organizations, resources, and processes that provide and distribute healthcare services and medical products. This chain includes pharmaceutical manufacturers, distribution companies, hospitals, pharmacies, healthcare centers, and patients. The primary objective of healthcare supply chain management is to ensure timely and effective access to healthcare resources at the lowest cost and with the highest quality. Unlike many other industries, the healthcare supply chain is highly sensitive because disruptions can directly affect patient health and safety <xref ref-type="bibr" rid="ref-4">[4]</xref>.</p>
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<sec id="sec-4"><label>2.2</label><title>Concept of Artificial Intelligence</title>
<p>AI refers to a collection of technologies and algorithms capable of performing tasks that typically require human intelligence. These technologies include machine learning, deep learning, natural language processing, expert systems, and data analytics. In recent years, advances in computational power and the rapid growth of digital data have significantly expanded the use of AI across various industries, particularly in healthcare <xref ref-type="bibr" rid="ref-5">[5]</xref>.</p>
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<sec id="sec-5"><label>2.3</label><title>Literature Review</title>
<p>Numerous studies have investigated the application of AI in healthcare supply chains. Researchers have shown that machine learning algorithms can improve the accuracy of pharmaceutical demand forecasting and prevent shortages or excessive inventory accumulation <xref ref-type="bibr" rid="ref-6">[6]</xref>. Moreover, the use of intelligent systems in the management of medical equipment distribution has reduced operational costs and improved responsiveness <xref ref-type="bibr" rid="ref-7">[7]</xref>. Several studies have also examined the role of AI in healthcare crisis management. Their findings indicate that AI-based systems can facilitate managerial decision-making during emergencies and optimize the allocation of healthcare resources <xref ref-type="bibr" rid="ref-8">[8]</xref>.</p>
<p>In addition, AI-based technologies can play a substantial role in identifying consumption patterns and analyzing patient behavior. The analysis of healthcare visitation records, disease prevalence, and pharmaceutical consumption trends enables healthcare managers to perform more accurate resource planning. This capability is particularly valuable during sudden increases in demand, as it can prevent disruptions in healthcare service delivery <xref ref-type="bibr" rid="ref-9">[9]</xref>.</p>
<p>On the other hand, intelligent systems enhance transparency and traceability throughout healthcare supply chain processes. These systems can continuously record and analyze data related to inventory levels, transportation activities, and medical equipment distribution. Consequently, managers can make faster, more accurate decisions while reducing the likelihood of human error, resource waste, and delivery delays <xref ref-type="bibr" rid="ref-10">[10]</xref>. In reality, many supply chain problems originate not from a lack of technology but from inconsistent human decision-making. An astonishing revelation, considering humans designed the systems and then seemed surprised when the systems behaved like humans .</p>
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<sec id="sec-6"><label>3</label><title>Applications of Artificial Intelligence in Healthcare Supply Chain Management</title>
<sec id="sec-7"><label>3.1</label><title>Forecasting Demand for Pharmaceuticals and Medical Equipment</title>
<p>One of the most significant applications of AI in healthcare supply chains is forecasting the demand for pharmaceuticals and medical equipment. Traditional forecasting methods are generally based on limited datasets and simple analytical techniques, which often lack sufficient accuracy under dynamic conditions. Machine learning algorithms can analyze historical data, seasonal patterns, disease trends, and consumer behavior to more accurately predict demand. This capability helps reduce pharmaceutical shortages, prevent excessive inventory accumulation, and decrease storage costs <xref ref-type="bibr" rid="ref-11">[11]</xref>.</p>
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<sec id="sec-8"><label>3.2</label><title>Intelligent Inventory Management</title>
<p>Inventory management is a major challenge for hospitals and healthcare centers. A shortage of medical equipment may endanger patient lives, while excessive inventory levels increase costs and waste resources. AI-based systems can monitor inventory status in real time and determine the optimal replenishment timing. By analyzing consumption patterns, pharmaceutical expiration dates, and crisis conditions, these systems provide more accurate inventory management decisions <xref ref-type="bibr" rid="ref-12">[12]</xref>.</p>
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<sec id="sec-9"><label>3.3</label><title>Optimization of Pharmaceutical and Medical Equipment Distribution</title>
<p>Another important application of AI is the optimization of pharmaceutical and medical equipment distribution networks. Intelligent algorithms can identify optimal transportation routes and reduce delivery times. This capability is especially critical in remote regions and emergencies. AI-based systems help reduce logistics costs, accelerate delivery processes, and improve patient access to healthcare services <xref ref-type="bibr" rid="ref-13">[13]</xref>.</p>
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<sec id="sec-10"><label>3.4</label><title>Healthcare Data Analytics and Decision Support</title>
<p>Healthcare centers generate enormous amounts of data daily. Manual analysis of such data is both time-consuming and difficult. AI can analyze healthcare data and provide valuable insights for managers. For example, intelligent algorithms can identify disease outbreak trends and predict future hospital needs for equipment and workforce resources. Such capabilities can significantly improve planning and resource allocation processes <xref ref-type="bibr" rid="ref-14">[14]</xref>.</p>
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<sec id="sec-11"><label>3.5</label><title>Risk Management in Healthcare Supply Chains</title>
<p>Healthcare supply chains are continuously exposed to risks such as global crises, shortages of raw materials, transportation disruptions, and market fluctuations. AI can analyze environmental data and identify risk patterns to predict potential disruptions. This argument enables managers to implement preventive measures before crises occur, thereby minimizing interruptions in healthcare service delivery <xref ref-type="bibr" rid="ref-15">[15]</xref>.</p>
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<sec id="sec-12"><label>4</label><title>Advantages of Using Artificial Intelligence in Healthcare Supply</title>
<p>The adoption of AI technologies in healthcare supply chain management offers numerous advantages, including the following :</p>
<sec id="sec-13"><label>4.1</label><title>Cost Reduction</title>
<p>AI optimizes procurement, storage, and distribution processes, thereby reducing operational costs. Minimizing resource waste and improving inventory management also play a substantial role in reducing costs <xref ref-type="bibr" rid="ref-16">[16]</xref>.</p>
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<sec id="sec-14"><label>4.2</label><title>Improved Decision-Making Accuracy</title>
<p>Intelligent algorithms can analyze large volumes of data and make more accurate decisions than traditional methods. This argument improves the quality of hospital and healthcare center management <xref ref-type="bibr" rid="ref-17">[17]</xref>.</p>
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<sec id="sec-15"><label>4.3</label><title>Increased Responsiveness</title>
<p>The use of intelligent systems accelerates managerial processes and reduces response times during critical situations <xref ref-type="bibr" rid="ref-17">[17]</xref>.</p>
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<sec id="sec-16"><label>4.4</label><title>Improved Quality of Healthcare Services</title>
<p>When pharmaceuticals and medical equipment are available on time, the quality of healthcare services improves, and patient satisfaction increases accordingly <xref ref-type="bibr" rid="ref-18">[18]</xref>.</p>
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<sec id="sec-17"><label>4.5</label><title>Enhanced Transparency and Traceability</title>
<p>AI can accurately record and analyze healthcare supply chain processes, resulting in greater transparency and reduced managerial errors <xref ref-type="bibr" rid="ref-18">[18]</xref>.</p>
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<sec id="sec-18"><label>5</label><title>Challenges of Using Artificial Intelligence in Healthcare Supply</title>
<p>Despite its numerous advantages, implementing AI in healthcare also presents several challenges.</p>
<sec id="sec-19"><label>5.1</label><title>High Implementation Costs</title>
<p>Designing and implementing AI-based systems requires significant investment in information technology infrastructure, software systems, and workforce training <xref ref-type="bibr" rid="ref-19">[19]</xref>.</p>
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<sec id="sec-20"><label>5.2</label><title>Data Security and Privacy Concerns</title>
<p>Healthcare data are highly sensitive. The use of AI systems may raise concerns regarding information security and patient privacy protection <xref ref-type="bibr" rid="ref-20">[20]</xref>.</p>
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<sec id="sec-21"><label>5.3</label><title>Shortage of Skilled Professionals</title>
<p>Many healthcare institutions face a shortage of specialists in data science and AI. This issue can hinder the implementation of intelligent technologies <xref ref-type="bibr" rid="ref-21">[21]</xref>.</p>
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<sec id="sec-22"><label>5.4</label><title>Organizational Resistance to Change</title>
<p>Some healthcare organizations and employees resist adopting new technologies. Such resistance may obstruct the development and implementation of AI-based systems <xref ref-type="bibr" rid="ref-22">[22]</xref>.</p>
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<sec id="sec-23"><label>6</label><title>Future of Artificial Intelligence in Healthcare Supply Chains</title>
<p>With the advancement of digital technologies, the role of AI in healthcare supply chain management is expected to expand significantly in the coming years. The development of the Internet of Things (IoT), big data analytics, cloud computing, and advanced data analysis technologies can facilitate the creation of intelligent healthcare supply chains. In the future, hospitals and healthcare centers may use intelligent systems to predict healthcare demand in real time and automatically manage resources. Furthermore, robots and automated systems are expected to play a greater role in logistics operations and the distribution of medical equipment <xref ref-type="bibr" rid="ref-23">[23]</xref>. Humans spent centuries building bureaucratic bottlenecks only to invent algorithms whose primary task is cleaning up after them. Progress has a sense of humor <xref ref-type="bibr" rid="ref-23">[23]</xref>.</p>
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<sec id="sec-24"><label>7</label><title>Conclusion</title>
<p>Healthcare supply chain management is one of the most influential factors affecting the quality of healthcare services and the efficiency of healthcare organizations. The growing complexity of healthcare processes and the increasing demand for medical services have made traditional management methods insufficient for modern healthcare systems .</p>
<p>The findings of this study demonstrate that AI can play a vital role in improving healthcare supply chain performance. Applications such as demand forecasting, intelligent inventory management, distribution optimization, healthcare data analytics, and risk management can reduce operational costs, accelerate decision-making processes, and improve the quality of healthcare services .</p>
<p>Despite challenges such as implementation costs, security concerns, and shortages of skilled professionals, the rapid development of AI technologies indicates that AI will become one of the fundamental pillars of healthcare system management in the future.</p>
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<sec id="sec-25"><title>Funding</title>
<p>This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.</p>
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<sec id="sec-26"><title>Data Availability</title>
<p>All data are included in the text.</p>
</sec>
<sec id="sec-27"><title>Conflicts of Interest</title>
<p>The authors declare no conflict of interest.</p>
</sec>
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<back><ref-list><title>References</title>
<ref id="ref-1"><label>1</label><mixed-citation>Zamlynskyi, V., Kalinichenko, S., Kniazkova, V., Skrypnyk, N., &amp; Avriata, A. (2025). Healthcare management using artificial intelligence. In Revolutionizing medical systems using artificial intelligence (pp. 1–24). Elsevier. <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.1016/B978-0-443-32862-6.00001-8">https://doi.org/10.1016/B978-0-443-32862-6.00001-8</ext-link></mixed-citation></ref>
<ref id="ref-2"><label>2</label><mixed-citation>Raj, A., Mukherjee, A. A., de Sousa Jabbour, A. B. L., &amp; Srivastava, S. K. (2022). Supply chain management during and post-COVID-19 pandemic: Mitigation strategies and practical lessons learned. Journal of business research, 142, 1125–1139. <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.1016/j.jbusres.2022.01.037">https://doi.org/10.1016/j.jbusres.2022.01.037</ext-link></mixed-citation></ref>
<ref id="ref-3"><label>3</label><mixed-citation>Ivanov, D., &amp; Dolgui, A. (2021). A digital supply chain twin for managing the disruption risks and resilience in the era of Industry 4.0. Production planning and control, 32(9), 775–788.</mixed-citation></ref>
<ref id="ref-4"><label>4</label><mixed-citation>Hofmann, E. (2013). Supply chain management: Strategy, planning and operation, s. chopra, p. meindl. Journal of purchasing and supply management, 19(3), 212–213. <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.1016/j.pursup.2013.07.003">https://doi.org/10.1016/j.pursup.2013.07.003</ext-link></mixed-citation></ref>
<ref id="ref-5"><label>5</label><mixed-citation>Lee, H. L. (2004). The triple-A supply chain. Harvard business review, 82(10), 102–113. <ext-link ext-link-type="uri" xlink:href="https://pubmed.ncbi.nlm.nih.gov/15559579/">https://pubmed.ncbi.nlm.nih.gov/15559579/</ext-link></mixed-citation></ref>
<ref id="ref-6"><label>6</label><mixed-citation>Ahmed, Z., Mohamed, K., Zeeshan, S., &amp; Dong, X. (2020). Artificial intelligence with multi-functional machine learning platform development for better healthcare and precision medicine. Database, 2020, baaa010. <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.1093/database/baaa010">https://doi.org/10.1093/database/baaa010</ext-link></mixed-citation></ref>
<ref id="ref-7"><label>7</label><mixed-citation>Kwon, I. W. G., Kim, S. H., &amp; Martin, D. G. (2016). Healthcare supply chain management; strategic areas for quality and financial improvement. Technological forecasting and social change, 113, 422–428. <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.1016/j.techfore.2016.07.014">https://doi.org/10.1016/j.techfore.2016.07.014</ext-link></mixed-citation></ref>
<ref id="ref-8"><label>8</label><mixed-citation>Min, H. (2010). Artificial intelligence in supply chain management: theory and applications. International journal of logistics: research and applications, 13(1), 13–39. <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.1080/13675560902736537">https://doi.org/10.1080/13675560902736537</ext-link></mixed-citation></ref>
<ref id="ref-9"><label>9</label><mixed-citation>Wang, Y., Kung, L., &amp; Byrd, T. A. (2018). Big data analytics: Understanding its capabilities and potential benefits for healthcare organizations. Technological forecasting and social change, 126, 3–13. <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.1016/j.techfore.2015.12.019">https://doi.org/10.1016/j.techfore.2015.12.019</ext-link></mixed-citation></ref>
<ref id="ref-10"><label>10</label><mixed-citation>Christopher, M. (2022). Logistics and supply chain management. Pearson Uk. <ext-link ext-link-type="uri" xlink:href="https://www.amazon.co.uk/Logistics-Supply-Management-Martin-Christopher/dp/1292416181">https://www.amazon.co.uk/Logistics-Supply-Management-Martin-Christopher/dp/1292416181</ext-link></mixed-citation></ref>
<ref id="ref-11"><label>11</label><mixed-citation>Tekkeşin, A. İ. (2019). Artificial intelligence in healthcare: Past, present and future. Anatol j cardiol, 22(Suppl 2), 8–9. 10.14744/AnatolJCardiol.2019.28661</mixed-citation></ref>
<ref id="ref-12"><label>12</label><mixed-citation>Akande, S. A., &amp; Enyejo, J. O. (2023). Artificial intelligence in supply chain management: A systematic review of emerging trends and evidence in healthcare operations. International journal of scientific research and modern technology, 3(12), 257–272. <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.38124/ijsrmt.v3i12.1055">https://doi.org/10.38124/ijsrmt.v3i12.1055</ext-link></mixed-citation></ref>
<ref id="ref-13"><label>13</label><mixed-citation>Nabayiga, H., Van Der Meer, R., &amp; Agha, M. S. A. (2025). A systematic review of simulation models in medicine supply chain management: Current state and emerging trends. Decision analytics journal, 14, 100555. <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.1016/j.dajour.2025.100555">https://doi.org/10.1016/j.dajour.2025.100555</ext-link></mixed-citation></ref>
<ref id="ref-14"><label>14</label><mixed-citation>Francis, J. R. (2020). COVID-19: implications for supply chain management. Frontiers of health services management, 37(1), 33–38. <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.1097/hap.0000000000000092">https://doi.org/10.1097/hap.0000000000000092</ext-link></mixed-citation></ref>
<ref id="ref-15"><label>15</label><mixed-citation>Nwamekwe, C. O., &amp; Igbokwe, N. C. (2024). Supply chain risk management: leveraging AI for risk identification, mitigation, and resilience planning. International journal of industrial engineering, technology &amp; operations management, 2(2), 41–51. <ext-link ext-link-type="uri" xlink:href="https://dx.doi.org/10.62157/ijietom.v2i2.38">https://dx.doi.org/10.62157/ijietom.v2i2.38</ext-link></mixed-citation></ref>
<ref id="ref-16"><label>16</label><mixed-citation>Helo, P., &amp; Hao, Y. (2022). Artificial intelligence in operations management and supply chain management: an exploratory case study. Production planning &amp; control, 33(16), 1573–1590.</mixed-citation></ref>
<ref id="ref-17"><label>17</label><mixed-citation>Mohsen, B. M. (2023). Impact of artificial intelligence on supply chain management performance. Journal of service science and management, 16(1), 44–58. <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.4236/jssm.2023.161004">https://doi.org/10.4236/jssm.2023.161004</ext-link></mixed-citation></ref>
<ref id="ref-18"><label>18</label><mixed-citation>Hassouna, M., El-henawy, I., &amp; Haggag, R. (2022). A multi-objective optimization for supply chain management using artificial intelligence (AI). International journal of advanced computer science and applications, 13(8), 140–149. <ext-link ext-link-type="uri" xlink:href="https://dx.doi.org/10.14569/IJACSA.2022.0130817">https://dx.doi.org/10.14569/IJACSA.2022.0130817</ext-link></mixed-citation></ref>
<ref id="ref-19"><label>19</label><mixed-citation>Baryannis, G., Validi, S., Dani, S., &amp; Antoniou, G. (2019). Supply chain risk management and artificial intelligence: state of the art and future research directions. International journal of production research, 57(7), 2179–2202. <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.1080/00207543.2018.1530476">https://doi.org/10.1080/00207543.2018.1530476</ext-link></mixed-citation></ref>
<ref id="ref-20"><label>20</label><mixed-citation>Samuels, A. (2025). Examining the integration of artificial intelligence in supply chain management from Industry 4.0 to 6.0: A systematic literature review. Frontiers in artificial intelligence, 7, 1477044. <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.3389/frai.2024.1477044">https://doi.org/10.3389/frai.2024.1477044</ext-link></mixed-citation></ref>
<ref id="ref-21"><label>21</label><mixed-citation>Nicoletti, B., &amp; Appolloni, A. (2025). The impact of AI foundation models on the future of digital engineering for logistics and supply chain. Digital engineering, 7, 100058. <ext-link ext-link-type="uri" xlink:href="https://doi.org/10.1016/j.dte.2025.100058">https://doi.org/10.1016/j.dte.2025.100058</ext-link></mixed-citation></ref>
<ref id="ref-22"><label>22</label><mixed-citation>Goswami, S. S., Mondal, S., Sarkar, S., Gupta, K. K., Sahoo, S. K., &amp; Halder, R. (2025). Artificial intelligence-enabled supply chain management: unlocking new opportunities and challenges [presentation]. Artificial intelligence and applications (Vol. 3, pp. 110–121). <ext-link ext-link-type="uri" xlink:href="https://orcid.org/0000-0002-0033-3089">https://orcid.org/0000-0002-0033-3089</ext-link></mixed-citation></ref>
<ref id="ref-23"><label>23</label><mixed-citation>Kagalwala, H., Radhakrishnan, G. V, Mohammed, I. A., Kothinti, R. R., &amp; Kulkarni, N. (2025). Predictive analytics in supply chain management: The role of AI and machine learning in demand forecasting. Advances in consumer research, 2(1), 142–149. file:///C:/Users/Administrator/Desktop/ACR-12.pdf</mixed-citation></ref>
</ref-list></back>
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